Resident Evil 4 Wii Edition - Completion bonuses

Successfully complete the game under the Professional mode to unlock the PRL 412 weapon.

Successfully complete Separate Ways mode to unlock Ashley's armored knight and Leon's suit alternate costumes.

Successfully complete Assignment Ada mode to unlock the Chicago Typewriter weapon.

Successfully complete Mercenaries mode with all characters with a five star rank to unlock the Handcannon weapon.

Mercenaries Bonus characters:
Get a four star or higher rank in the indicated Mercenaries mode level to unlock the corresponding character in Mercenaries mode.

Ada Wong: Pueblo
Albert Wesker: Waterworld
Hunk: Island
Jack Krauser: Castle

Hidden cinematics:
There are two hidden cinematics accessible at the title screen. One can be accessed by remaining idle at the main menu until it starts. The other can be seen by pressing B on the Wiimote at the same menu.

Open doors faster:
Tap A2 when the "Open" command appears by a door to kick it open quickly. Doing this will also damage any enemies behind the door at the time you kick.

Defeating the Regenerator:
If you find your rifle is empty, you can also defeat the Regenerator by shooting a mine into the spot around the parasite. If it is on its back, just shoot out its legs with your handgun then fire a mine into its back. If this does not work, scout out where the parasite is on the Regenerator and try again.

Spinel:
When enter the bedroom after the garden, look on the roof of the bed. You should see a sparkling object. It is a spinel.